Occlusion of which artery is most commonly associated with an anterior wall infarction?

• A. Right Coronary
• B. Left Circumflex
• C. Left Anterior Descending
• D. Posterior Descending

Answer: (C)

The vessel that most commonly causes an anterior wall infarction is the left anterior descending artery. The LAD travels down the anterior interventricular groove and supplies the majority of the anterior left ventricle and much of the anterior septum. When it becomes occluded, the large anterior myocardial territory becomes ischemic, leading to an anterior wall MI. This pattern often shows ST elevations in the anterior leads (V1–V4) on the ECG. Other arteries tend to affect different regions: the right coronary artery usually causes inferoposterior involvement, the left circumflex tends to cause lateral wall infarction, and the posterior descending artery is linked to the posterior/inferior wall depending on coronary dominance.